|
Mutation Information
|
Mutation Site
|
Y143C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
INSTIs |
|
Country
|
Cameroon |
Literature Information
|
PubMed PMID
|
32954411
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon. |
|
Author
|
Wenk BM,Mbunkah HA,Nsanwe NN,Mbu ET,Besong LM,Sama BA,Orock E,Leemann C,Metzner KJ |
|
Evidence
|
At low abundance (frequency between 3% and 15%), 3/255 (1.2%) individuals each harboured one major INSTI DRM: E138K (4.4%), G140S (5.7%) and Y143C (9.0%) (Table 2).
|
|
|
HIV Mutation Detail Information