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Mutation Information
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Mutation Site
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Y143G |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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IN |
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Relevant Drug
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INSTIs |
Literature Information
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PubMed PMID
|
31965175
|
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Disease
|
HIV infection/AIDS
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Published Year
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2020 |
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Journal
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The Journal of infectious diseases |
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Title
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Expanded Spectrum of Antiretroviral-Selected Mutations in Human Immunodeficiency Virus Type 2. |
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Author
|
Tzou PL,Descamps D,Rhee SY,Raugi DN,Charpentier C,Taveira N,Smith RA,Soriano V,de Mendoza C,Holmes SP,Gottlieb GS,Shafer RW |
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Evidence
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In PR, 12 nonpolymorphic TSMs occurred in >=11 persons: V33I, K45R, V47A, I50V, I54M, T56V, V62A, A73G, I82F, I84V, F85L, L90M. In RT, 9 nonpolymorphic TSMs occurred in >=10 persons: K40R, A62V, K70R, Y115F, Q151M, M184VI, S215Y. In IN, 11 nonpolymorphic TSMs occurred in >=4 persons: Q91R, E92AQ, T97A, G140S, Y143G, Q148R, A153G, N155H, H156R, R231 5-amino acid insertions.
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