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Mutation Information
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Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
NRTIs |
Literature Information
|
PubMed PMID
|
17500586
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2007 |
|
Journal
|
PLoS computational biology |
|
Title
|
HIV-1 subtype B protease and reverse transcriptase amino acid covariation. |
|
Author
|
Rhee SY,Liu TF,Holmes SP,Shafer RW |
|
Evidence
|
The strongest significant association between an NRTI and an NNRTI mutation was between L74V and Y181C (J = 0.17, Z = 8.9, unadjusted p < 1 × 10−11).
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HIV Mutation Detail Information