|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
29975689
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
PloS one |
|
Title
|
HIV-1 diversity among young women in rural South Africa: HPTN 068. |
|
Author
|
Sivay MV,Hudelson SE,Wang J,Agyei Y,Hamilton EL,Selin A,Dennis A,Kahn K,Gomez-Olive FX,MacPhail C,Hughes JP,Pettifor A,Eshleman SH,Grabowski MK |
|
Evidence
|
At least one major non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistance mutation (K103N, V106M, Y181C, G190A/S) was detected in 19 sequences;five of those sequences also had the M184V nucleoside reverse transcriptase inhibitor (NRTI)-resistance mutation.
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HIV Mutation Detail Information