|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
tenofovir (TDF);emtricitabine (FTC) |
|
Country
|
france |
Literature Information
|
PubMed PMID
|
32642769
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
Persistent low-level viraemia in antiretroviral treatment-experienced patients is not linked to viral resistance or inadequate drug concentrations. |
|
Author
|
Palich R,Wirden M,Peytavin G,Lê MP,Seang S,Abdi B,Schneider L,Tubiana R,Valantin MA,Paccoud O,Soulié C,Calvez V,Katlama C,Marcelin AG |
|
Evidence
|
The four virological failures were due to three ART interruptions and one incomplete adherence (selection of Y181C RAM).
|
|
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HIV Mutation Detail Information