|
Mutation Information
|
Mutation Site
|
Y18F |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
Literature Information
|
PubMed PMID
|
32882910
|
|
Published Year
|
2020 |
|
Journal
|
Viruses |
|
Title
|
Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2. |
|
Author
|
Wang Q,Fu S,Zhang J,Yuan Q,Li J,Xia N,Wen YM,Wang Y,Tong S |
|
Evidence
|
Of the three single point mutations, V19A and to a lesser extent Y18F increased intracellular HBsAg to reduce the ratio of extracellular/intracellular HBsAg, while A17G had limited effect (Figure 11A-C).
|
|
|
HBV Mutation Detail Information