|
Mutation Information
|
Mutation Site
|
Y195V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
B |
Literature Information
|
PubMed PMID
|
12171302
|
|
Disease
|
HBV infection
|
|
Published Year
|
2002 |
|
Journal
|
Journal of medical microbiology |
|
Title
|
Identification of a new variant in the YMDD motif of the hepatitis B virus polymerase gene selected during lamivudine therapy. |
|
Author
|
Niesters HGM,DE Man RA,Pas SD,Fries E,Osterhaus ADME |
|
Evidence
|
This change simultaneously resulted in a tyrosine-195 into valine variant (sY195V) in the surface protein HBsAg.
|
|
|