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Mutation Information
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Mutation Site
|
Y26A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tat |
Literature Information
|
PubMed PMID
|
32824587
|
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Published Year
|
2020 |
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Journal
|
International journal of molecular sciences |
|
Title
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Y44A Mutation in the Acidic Domain of HIV-2 Tat Impairs Viral Reverse Transcription and LTR-Transactivation. |
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Author
|
Szojka Z,Mótyán JA,Miczi M,Mahdi M,Tőzsér J |
|
Evidence
|
It was previously reported that the transcription activation function of HIV-1 Tat can be abolished upon Y26A and SIV (simian immunodeficiency virus) Tat by Y55A amino acid substitutions.
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HIV Mutation Detail Information