HPV Mutation Detail Information

> Y379F Search Result

Mutation Information

Mutation Site	Y379F
Mutation Type	Amino acid level
Gene/Protein/Region Type	E1
Genotype/Subtype	HPV16
Viral Reference	K02718.1
Country	Japan

Literature Information

PubMed PMID	24236186
Disease	High grade squamous intraepithelial lesion; Low grade squamous intraepithelial lesion; Cervical carcinoma
Published Year	2013
Journal	PloS one
Title	Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing.
Author	Kukimoto I,Maehama T,Sekizuka T,Ogasawara Y,Kondo K,Kusumoto-Matsuo R,Mori S,Ishii Y,Takeuchi T,Yamaji T,Takeuchi F,Hanada K,Kuroda M
Evidence	The E1 mutant Y379F (in which tyrosine at 379 is replaced with phenylalanine), which is expected to lose replication activity as reported previously [38], was also included as a representative of a replication-deficient E1 protein.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation