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Mutation Information
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Mutation Site
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Y44A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tat |
Literature Information
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PubMed PMID
|
32824587
|
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Published Year
|
2020 |
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Journal
|
International journal of molecular sciences |
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Title
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Y44A Mutation in the Acidic Domain of HIV-2 Tat Impairs Viral Reverse Transcription and LTR-Transactivation. |
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Author
|
Szojka Z,Mótyán JA,Miczi M,Mahdi M,Tőzsér J |
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Evidence
|
Here, we describe Y44A-inactivating mutation of HIV-2 Tat, studying its effect on capsid production, reverse transcription, and the efficiency of proviral transcription.
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