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Mutation Information
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Mutation Site
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Y63F |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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RT |
Literature Information
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PubMed PMID
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32650547
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Published Year
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2020 |
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Journal
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Viruses |
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Title
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Phosphorylation of the Arginine-Rich C-Terminal Domains of the Hepatitis B Virus (HBV) Core Protein as a Fine Regulator of the Interaction between HBc and Nucleic Acid. |
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Author
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de Rocquigny H,Rat V,Pastor F,Darlix JL,Hourioux C,Roingeard P |
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Evidence
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Firstly, it was found that unassembled capsids were hyper-phosphorylated, in agreement with the phosphorylation status of empty capsids, while assembled capsids, produced from pgRNA encoding for the Y63F mutant DNA polymerase and containing only pgRNA, were mainly hypo-phosphorylated.
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HBV Mutation Detail Information