HBV Target gene Detail Information

> ABCB8 Gene Search Result

Gene Information

Gene Name	ABCB8
Gene ID	11194
Gene Full Name	ATP binding cassette subfamily B member 8
Gene Alias	MABC1; M-ABC1; EST328128
Transcripts	ENSG00000197150
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9NUT2
HGNC ID	HGNC:49
VEGA ID	OTTHUMG00000158686
OMIM ID	605464
String ID	9606.ENSP00000297504
Drugbank ID	BE0003673
PharmGKB ID	PA24390

Target gene [ABCB8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006072	chr7	44			44	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of ABCB8 expression and immune infiltrating cell level correlation result in HBV+ samples
ABCB8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).