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HBV Target gene Detail Information

> ADH1B Gene Search Result


Gene Information
Gene Name ADH1B
Gene ID 125
Gene Full Name alcohol dehydrogenase 1B (class I), beta polypeptide
Gene Alias ADH2; HEL-S-117
Transcripts ENSG00000196616
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID P00325
HGNC ID HGNC:250
VEGA ID OTTHUMG00000161413
OMIM ID 103720
String ID 9606.ENSP00000306606
Drugbank ID BE0000400
PharmGKB ID PA24571
Target gene [ADH1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008764 chr4 14 5 19 View
1010449 chr4 3 6 3 12 View
1010510 chr4 11 1 12 View
1010574 chr4 4 7 11 View
1016205 chr4 1 1 View
1017261 chr4 1 1 View
1018175 chr4 0 View
1018664 chr4 0 View
1019759 chr4 0 View
1404281 chr4 1 1 View
1404816 chr4 0 View
1404828 chr4 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ADH1B expression and immune infiltrating cell level correlation result in HBV+ samples
ADH1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).