HIV Target gene Detail Information

> AP3S1 Gene Search Result

Gene Information

Gene Name	AP3S1
Gene ID	1176
Gene Full Name	adaptor related protein complex 3 subunit sigma 1
Gene Alias	CLAPS3; Sigma3A
Transcripts	ENSG00000177879
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q92572
HGNC ID	HGNC:2013
VEGA ID	OTTHUMG00000128887
OMIM ID	601507
String ID	9606.ENSP00000325369
PharmGKB ID	PA24862

Target gene [AP3S1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016380	chr5				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of AP3S1 expression and immune infiltrating cell level correlation result in HIV+ samples
AP3S1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of AP3S1 expression and immune infiltrating cell level correlation result in HIV+ samples
AP3S1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).