HBV Target gene Detail Information

> APOC3 Gene Search Result

Gene Information

Gene Name	APOC3
Gene ID	345
Gene Full Name	apolipoprotein C3
Gene Alias	APOCIII
Transcripts	ENSG00000110245
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cell Junctions;Nucleoli;Predicted to be secreted;
HPA Protein Class Info	Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID	P02656
HGNC ID	HGNC:610
VEGA ID	OTTHUMG00000046115
OMIM ID	107720
String ID	9606.ENSP00000227667
Drugbank ID	BE0005896
PharmGKB ID	PA53

Target gene [APOC3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005204	chr11	30	29		59	View
1007734	chr11	11	14		25	View
1010844	chr11	9	2		11	View
1011067	chr11	4	6		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of APOC3 expression and immune infiltrating cell level correlation result in HBV+ samples
APOC3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).