HIV Target gene Detail Information

> ARSB Gene Search Result

Gene Information

Gene Name	ARSB
Gene ID	411
Gene Full Name	arylsulfatase B
Gene Alias	ASB; G4S; MPS6
Transcripts	ENSG00000113273
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P15848
HGNC ID	HGNC:714
VEGA ID	OTTHUMG00000108129
OMIM ID	611542
String ID	9606.ENSP00000264914
Drugbank ID	BE0009298
PharmGKB ID	PA25006

Target gene [ARSB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004769	chr5	36	2	1	39	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of ARSB expression and immune infiltrating cell level correlation result in HIV+ samples
ARSB expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of ARSB expression and immune infiltrating cell level correlation result in HIV+ samples
ARSB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).