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HBV Target gene Detail Information

> BCAR3 Gene Search Result


Gene Information
Gene Name BCAR3
Gene ID 8412
Gene Full Name BCAR3, NSP family adaptor protein
Gene Alias NSP2; AND-34; SH2D3B
Transcripts ENSG00000137936
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;Centrosome;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O75815
HGNC ID HGNC:973
VEGA ID OTTHUMG00000010301
OMIM ID 604704
String ID 9606.ENSP00000359264
PharmGKB ID PA25283
Target gene [BCAR3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004001 chr1 55 13 29 97 View
1403326 chr1 55 13 29 97 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of BCAR3 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
BCAR3 expression: Low -> High
Lollipop of BCAR3 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of BCAR3 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of BCAR3 expression and immune infiltrating cell level correlation result in HBV+ samples
BCAR3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).