HBV Target gene Detail Information

> BCHE Gene Search Result

Gene Information

Gene Name	BCHE
Gene ID	590
Gene Full Name	butyrylcholinesterase
Gene Alias	E1; CHE1; CHE2; BCHED
Transcripts	ENSG00000114200
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P06276
HGNC ID	HGNC:983
VEGA ID	OTTHUMG00000158131
OMIM ID	177400
String ID	9606.ENSP00000264381
Drugbank ID	BE0002180
PharmGKB ID	PA25294
FDA Approved Drug	Mivacurium;Succinylcholine

Target gene [BCHE] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013991	chr3	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of BCHE expression and immune infiltrating cell level correlation result in HBV+ samples
BCHE expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).