HIV Target gene Detail Information

> BCL11B Gene Search Result

Gene Information

Gene Name	BCL11B
Gene ID	64919
Gene Full Name	BCL11B, BAF complex component
Gene Alias	ATL1; RIT1; CTIP2; IMD49; CTIP-2; IDDFSTA; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha
Transcripts	ENSG00000127152
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli fibrillar center;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	Q9C0K0
HGNC ID	HGNC:13222
VEGA ID	OTTHUMG00000028967
OMIM ID	606558
String ID	9606.ENSP00000349723
PharmGKB ID	PA25301

Target gene [BCL11B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000710	chr14	189	65	55	309	View
4001223	chr14	183	9		192	View
4002803	chr14	11	35	33	79	View
4004277	chr14	44	2		46	View
4004797	chr14	23	14	2	39	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of BCL11B expression and immune infiltrating cell level correlation result in HIV+ samples
BCL11B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of BCL11B expression and immune infiltrating cell level correlation result in HIV+ samples
BCL11B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).