HBV Target gene Detail Information

> BHLHE40 Gene Search Result

Gene Information

Gene Name	BHLHE40
Gene ID	8553
Gene Full Name	basic helix-loop-helix family member e40
Gene Alias	DEC1; HLHB2; BHLHB2; Clast5; SHARP2; STRA13; Stra14; SHARP-2
Transcripts	ENSG00000134107
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	O14503
HGNC ID	HGNC:1046
VEGA ID	OTTHUMG00000119035
OMIM ID	604256
String ID	9606.ENSP00000256495
PharmGKB ID	PA25347

Target gene [BHLHE40] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002276	chr3	286	16		302	View
1400262	chr3	100			100	View
1403812	chr9	2	14		16	View
1403813	chr9	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of BHLHE40 expression and immune infiltrating cell level correlation result in HBV+ samples
BHLHE40 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).