HBV Target gene Detail Information

> BRCA1 Gene Search Result

Gene Information

Gene Name	BRCA1
Gene ID	672
Gene Full Name	BRCA1, DNA repair associated
Gene Alias	IRIS; PSCP; BRCAI; BRCC1; FANCS; PNCA4; RNF53; BROVCA1; PPP1R53
Transcripts	ENSG00000012048
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P38398
HGNC ID	HGNC:1100
VEGA ID	OTTHUMG00000157426
OMIM ID	113705
String ID	9606.ENSP00000418960
PharmGKB ID	PA25411

Target gene [BRCA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010709	chr17	10	1		11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of BRCA1 expression and immune infiltrating cell level correlation result in HBV+ samples
BRCA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).