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HBV Target gene Detail Information

> BRI3BP Gene Search Result


Gene Information
Gene Name BRI3BP
Gene ID 140707
Gene Full Name BRI3 binding protein
Gene Alias KG19; BNAS1; HCCR-1; HCCR-2; HCCRBP-1; HCCRBP-3
Transcripts ENSG00000184992
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters
Uniport_ID Q8WY22
HGNC ID HGNC:14251
VEGA ID OTTHUMG00000168548
OMIM ID 615627
String ID 9606.ENSP00000340761
PharmGKB ID PA25423
Target gene [BRI3BP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000192 chr12 2483 947 949 4379 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of BRI3BP expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
BRI3BP expression: Low -> High
Lollipop of BRI3BP expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of BRI3BP expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of BRI3BP expression and immune infiltrating cell level correlation result in HBV+ samples
BRI3BP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).