HTLV1 Target gene Detail Information

> C19orf54 Gene Search Result

Gene Information

Gene Name	C19orf54
Gene ID	284325
Gene Full Name	chromosome 19 open reading frame 54
Transcripts	ENSG00000188493
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Intermediate filaments;Centriolar satellite;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5BKX5
HGNC ID	HGNC:24758
VEGA ID	OTTHUMG00000150174
String ID	9606.ENSP00000367564
PharmGKB ID	PA147358417

Target gene [C19orf54] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6026116	chr19	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of C19orf54 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C19orf54 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of C19orf54 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C19orf54 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).