HTLV1 Target gene Detail Information

> C5orf46 Gene Search Result

Gene Information

Gene Name	C5orf46
Gene ID	389336
Gene Full Name	chromosome 5 open reading frame 46
Gene Alias	SSSP1
Transcripts	ENSG00000178776
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Mitochondria;Predicted to be secreted;
HPA Protein Class Info	Predicted secreted proteins
Uniport_ID	Q6UWT4
HGNC ID	HGNC:33768
VEGA ID	OTTHUMG00000163420
String ID	9606.ENSP00000315370
PharmGKB ID	PA162380305

Target gene [C5orf46] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001999	chr5	95	124	83	302	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of C5orf46 expression and immune infiltrating cell level correlation result in HTLV1+ samples
C5orf46 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).