HBV Target gene Detail Information

> CAPZB Gene Search Result


Gene Information
Gene Name CAPZB
Gene ID 832
Gene Full Name capping actin protein of muscle Z-line subunit beta
Gene Alias CAPB; CAPZ; CAPPB
Transcripts ENSG00000077549
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Vesicles;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P47756
HGNC ID HGNC:1491
VEGA ID OTTHUMG00000002556
OMIM ID 601572
String ID 9606.ENSP00000401010
PharmGKB ID PA26072
Target gene [CAPZB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005572 chr1 35 8 8 51 View
1007402 chr1 8 3 16 27 View
1400518 chr1 225 17 23 265 View
1400519 chr1 227 17 25 269 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CAPZB expression and immune infiltrating cell level correlation result in HBV+ samples
CAPZB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).