HBV Target gene Detail Information

> CBFA2T2 Gene Search Result


Gene Information
Gene Name CBFA2T2
Gene ID 9139
Gene Full Name CBFA2/RUNX1 translocation partner 2
Gene Alias EHT; p85; MTGR1; ZMYND3
Transcripts ENSG00000078699
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID O43439
HGNC ID HGNC:1536
VEGA ID OTTHUMG00000032261
OMIM ID 603672
String ID 9606.ENSP00000262653
PharmGKB ID PA26112
Target gene [CBFA2T2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001863 chr20 218 114 117 449 View
1004896 chr20 66 66 View
1011858 chr20 6 2 8 View
1013429 chr20 4 1 5 View
1013430 chr20 4 1 5 View
1403640 chr20 66 66 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CBFA2T2 expression and immune infiltrating cell level correlation result in HBV+ samples
CBFA2T2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).