EBV Target gene Detail Information

> CCDC186 Gene Search Result

Gene Information

Gene Name	CCDC186
Gene ID	55088
Gene Full Name	coiled-coil domain containing 186
Gene Alias	CCCP-1; C10orf118; golgin104
Transcripts	ENSG00000165813
Virus	EBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q7Z3E2
HGNC ID	HGNC:24349
VEGA ID	OTTHUMG00000019081
OMIM ID	619249
String ID	9606.ENSP00000358293
PharmGKB ID	PA134904295

Target gene [CCDC186] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000601	chr10	5	4		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE100458 (GEO)	Burkitt lymphoma	14	Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO)	Burkitt lymphoma	12	Burkitt lymphoma cell line Awia (EBV+)(12)
GSE12452 (GEO)	Nasopharyngeal carcinoma	41	Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE100458
HeatMap of cell type fractions in all samples	Lollipop of CCDC186 expression and immune infiltrating cell level correlation result in EBV+ samples
CCDC186 expression: Low -> High

> Dataset: GSE42867
HeatMap of cell type fractions in all samples	Lollipop of CCDC186 expression and immune infiltrating cell level correlation result in EBV+ samples
CCDC186 expression: Low -> High

> Dataset: GSE12452
HeatMap of cell type fractions in all samples	Lollipop of CCDC186 expression and immune infiltrating cell level correlation result in EBV+ samples
CCDC186 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).