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HBV Target gene Detail Information

> CDC16 Gene Search Result


Gene Information
Gene Name CDC16
Gene ID 8881
Gene Full Name cell division cycle 16
Gene Alias APC6; CUT9; ANAPC6; CDC16Hs
Transcripts ENSG00000130177
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins
Uniport_ID Q13042
HGNC ID HGNC:1720
VEGA ID OTTHUMG00000017402
OMIM ID 603461
String ID 9606.ENSP00000353549
PharmGKB ID PA26256
Target gene [CDC16] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009737 chr13 14 14 View
1400407 chr13 166 2 168 View
1401893 chr13 14 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of CDC16 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
CDC16 expression: Low -> High
Lollipop of CDC16 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of CDC16 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CDC16 expression and immune infiltrating cell level correlation result in HBV+ samples
CDC16 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).