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EBV Target gene Detail Information

> CDK15 Gene Search Result


Gene Information
Gene Name CDK15
Gene ID 65061
Gene Full Name cyclin dependent kinase 15
Gene Alias PFTK2; ALS2CR7; PFTAIRE2
Transcripts ENSG00000138395
Virus EBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Golgi apparatus;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q96Q40
HGNC ID HGNC:14434
VEGA ID OTTHUMG00000132838
OMIM ID 616147
String ID 9606.ENSP00000406472
Drugbank ID BE0000437
PharmGKB ID PA165696414
Target gene [CDK15] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000577 chr2 11 11 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of CDK15 expression and immune infiltrating cell level correlation result in EBV+ samples
CDK15 expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of CDK15 expression and immune infiltrating cell level correlation result in EBV+ samples
CDK15 expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of CDK15 expression and immune infiltrating cell level correlation result in EBV+ samples
CDK15 expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of CDK15 expression and immune infiltrating cell level correlation result in EBV+ samples
CDK15 expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of CDK15 expression and immune infiltrating cell level correlation result in EBV+ samples
CDK15 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).