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HBV Target gene Detail Information

> CELSR1 Gene Search Result


Gene Information
Gene Name CELSR1
Gene ID 9620
Gene Full Name cadherin EGF LAG seven-pass G-type receptor 1
Gene Alias ME2; FMI2; CDHF9; HFMI2; ADGRC1
Transcripts ENSG00000075275
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID Q9NYQ6
HGNC ID HGNC:1850
VEGA ID OTTHUMG00000150423
OMIM ID 604523
String ID 9606.ENSP00000262738
PharmGKB ID PA26393
Target gene [CELSR1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004431 chr22 60 14 7 81 View
1403879 chr22 60 14 7 81 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CELSR1 expression and immune infiltrating cell level correlation result in HBV+ samples
CELSR1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).