HIV Target gene Detail Information

> CHSY1 Gene Search Result

Gene Information

Gene Name	CHSY1
Gene ID	22856
Gene Full Name	chondroitin sulfate synthase 1
Gene Alias	CHSY; CSS1; TPBS; ChSy-1
Transcripts	ENSG00000131873
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins
Uniport_ID	Q86X52
HGNC ID	HGNC:17198
VEGA ID	OTTHUMG00000149873
OMIM ID	608183
String ID	9606.ENSP00000254190
PharmGKB ID	PA26509

Target gene [CHSY1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002719	chr15	77	5		82	View
4003649	chr15	53	4		57	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CHSY1 expression and immune infiltrating cell level correlation result in HIV+ samples
CHSY1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CHSY1 expression and immune infiltrating cell level correlation result in HIV+ samples
CHSY1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).