HBV Target gene Detail Information

> CIT Gene Search Result

Gene Information

Gene Name	CIT
Gene ID	11113
Gene Full Name	citron rho-interacting serine/threonine kinase
Gene Alias	CITK; CRIK; STK21; MCPH17
Transcripts	ENSG00000122966
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	O14578
HGNC ID	HGNC:1985
VEGA ID	OTTHUMG00000134325
OMIM ID	605629
String ID	9606.ENSP00000376306
Drugbank ID	BE0002685; BE0009378
PharmGKB ID	PA26522

Target gene [CIT] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003424	chr12	32	33	70	135	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CIT expression and immune infiltrating cell level correlation result in HBV+ samples
CIT expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).