Home
Virus
Gene
Disease
Dataset
Download
Help
 
HTLV1 Target gene Detail Information

> COL4A2 Gene Search Result


Gene Information
Gene Name COL4A2
Gene ID 1284
Gene Full Name collagen type IV alpha 2 chain
Gene Alias ICH; POREN2
Transcripts ENSG00000134871
Virus HTLV1
Gene Type protein coding
HPA Location Info Vesicles;Predicted to be secreted;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P08572
HGNC ID HGNC:2203
VEGA ID OTTHUMG00000017344
OMIM ID 120090
String ID 9606.ENSP00000353654
PharmGKB ID PA26718
Target gene [COL4A2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001085 chr13 150 132 315 597 View
6002646 chr13 66 90 65 221 View
6015327 chr13 11 3 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of COL4A2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COL4A2 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of COL4A2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COL4A2 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of COL4A2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COL4A2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).