HBV Target gene Detail Information

> COPA Gene Search Result

Gene Information

Gene Name	COPA
Gene ID	1314
Gene Full Name	coatomer protein complex subunit alpha
Gene Alias	AILJK; HEP-COP
Transcripts	ENSG00000122218
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Golgi apparatus;Predicted to be secreted;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P53621
HGNC ID	HGNC:2230
VEGA ID	OTTHUMG00000033111
OMIM ID	601924
String ID	9606.ENSP00000357048
Rfam ID	RF00042
PharmGKB ID	PA26746

Target gene [COPA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000088	chr1	3994	2368	1161	7523	View
1006805	chr1	20	7	7	34	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of COPA expression and immune infiltrating cell level correlation result in HBV+ samples
COPA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).