HBV Target gene Detail Information

> CTNNA3 Gene Search Result


Gene Information
Gene Name CTNNA3
Gene ID 29119
Gene Full Name catenin alpha 3
Gene Alias VR22; ARVD13
Transcripts ENSG00000183230
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9UI47
HGNC ID HGNC:2511
VEGA ID OTTHUMG00000018334
OMIM ID 607667
String ID 9606.ENSP00000389714
PharmGKB ID PA27010
Target gene [CTNNA3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005124 chr10 60 1 61 View
1012313 chr10 1 6 7 View
1400358 chr10 0 View
1400359 chr10 101 19 11 131 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CTNNA3 expression and immune infiltrating cell level correlation result in HBV+ samples
CTNNA3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).