HIV Target gene Detail Information

> DEPDC5 Gene Search Result

Gene Information

Gene Name	DEPDC5
Gene ID	9681
Gene Full Name	DEP domain containing 5
Gene Alias	DEP.5; FFEVF; FFEVF1
Transcripts	ENSG00000100150
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	O75140
HGNC ID	HGNC:18423
VEGA ID	OTTHUMG00000030926
OMIM ID	614191
String ID	9606.ENSP00000383105
PharmGKB ID	PA134864958

Target gene [DEPDC5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002644	chr22	36	22	28	86	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DEPDC5 expression and immune infiltrating cell level correlation result in HIV+ samples
DEPDC5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DEPDC5 expression and immune infiltrating cell level correlation result in HIV+ samples
DEPDC5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).