HPV Target gene Detail Information

> DMRTA1 Gene Search Result

Gene Information

Gene Name	DMRTA1
Gene ID	63951
Gene Full Name	DMRT like family A1
Gene Alias	DMO; DMRT4
Transcripts	ENSG00000176399
Virus	HPV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q5VZB9
HGNC ID	HGNC:13826
VEGA ID	OTTHUMG00000019693
OMIM ID	614803
String ID	9606.ENSP00000319651
PharmGKB ID	PA27384

Target gene [DMRTA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402755	chr9	1	4	6	11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55542 (GEO)	Oropharyngeal squamous cell carcinoma	36	Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of DMRTA1 expression and immune infiltrating cell level correlation result in HPV+ samples
DMRTA1 expression: Low -> High

> Dataset: GSE55542
HeatMap of cell type fractions in all samples	Lollipop of DMRTA1 expression and immune infiltrating cell level correlation result in HPV+ samples
DMRTA1 expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of DMRTA1 expression and immune infiltrating cell level correlation result in HPV+ samples
DMRTA1 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of DMRTA1 expression and immune infiltrating cell level correlation result in HPV+ samples
DMRTA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).