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EBV Target gene Detail Information

> DPH1 Gene Search Result


Gene Information
Gene Name DPH1
Gene ID 1801
Gene Full Name diphthamide biosynthesis 1
Gene Alias DPH2L; OVCA1; DEDSSH; DPH2L1
Transcripts ENSG00000108963
Virus EBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cell Junctions;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9BZG8
HGNC ID HGNC:3003
VEGA ID OTTHUMG00000177724
OMIM ID 603527
String ID 9606.ENSP00000263083
PharmGKB ID PA27461
Target gene [DPH1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000007 chr17 3207 1100 620 4927 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE135644 (GEO) Gastric carcinoma 10 Gastric adenocarcinoma cell line AGS (5), Gastric adenocarcinoma cell line AGS (EBV+)(5)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of DPH1 expression and immune infiltrating cell level correlation result in EBV+ samples
DPH1 expression: Low -> High

> Dataset: GSE135644

HeatMap of cell type fractions in all samples Lollipop of DPH1 expression and immune infiltrating cell level correlation result in EBV+ samples
DPH1 expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of DPH1 expression and immune infiltrating cell level correlation result in EBV+ samples
DPH1 expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of DPH1 expression and immune infiltrating cell level correlation result in EBV+ samples
DPH1 expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of DPH1 expression and immune infiltrating cell level correlation result in EBV+ samples
DPH1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).