EBV Target gene Detail Information

> DYTN Gene Search Result

Gene Information

Gene Name	DYTN
Gene ID	391475
Gene Full Name	dystrotelin
Transcripts	ENSG00000232125
Virus	EBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	A2CJ06
HGNC ID	HGNC:23279
VEGA ID	OTTHUMG00000154729
OMIM ID	618510
String ID	9606.ENSP00000396593
PharmGKB ID	PA162384136

Target gene [DYTN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000750	chr2	3	2		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE102203 (GEO)	B-cell lymphoma	9	Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE45919 (GEO)	Infectious mononucleosis	24	Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO)	Infectious mononucleosis	17	Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO)	Multiple sclerosis	32	Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)

> Dataset: GSE102203
HeatMap of cell type fractions in all samples	Lollipop of DYTN expression and immune infiltrating cell level correlation result in EBV+ samples
DYTN expression: Low -> High

> Dataset: GSE45919
HeatMap of cell type fractions in all samples	Lollipop of DYTN expression and immune infiltrating cell level correlation result in EBV+ samples
DYTN expression: Low -> High

> Dataset: GSE85599
HeatMap of cell type fractions in all samples	Lollipop of DYTN expression and immune infiltrating cell level correlation result in EBV+ samples
DYTN expression: Low -> High

> Dataset: GSE58240
HeatMap of cell type fractions in all samples	Lollipop of DYTN expression and immune infiltrating cell level correlation result in EBV+ samples
DYTN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).