HIV Target gene Detail Information

> EIF3K Gene Search Result

Gene Information

Gene Name	EIF3K
Gene ID	27335
Gene Full Name	eukaryotic translation initiation factor 3 subunit K
Gene Alias	M9; ARG134; PLAC24; PTD001; EIF3S12; HSPC029; MSTP001; PLAC-24; PRO1474; EIF3-p28
Transcripts	ENSG00000282986
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9UBQ5
HGNC ID	HGNC:24656
VEGA ID	OTTHUMG00000180865
OMIM ID	609596
String ID	9606.ENSP00000248342
PharmGKB ID	PA162384923

Target gene [EIF3K] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007323	chr19	20			20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of EIF3K expression and immune infiltrating cell level correlation result in HIV+ samples
EIF3K expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of EIF3K expression and immune infiltrating cell level correlation result in HIV+ samples
EIF3K expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).