HBV Target gene Detail Information

> EIF4G3 Gene Search Result

Gene Information

Gene Name	EIF4G3
Gene ID	8672
Gene Full Name	eukaryotic translation initiation factor 4 gamma 3
Gene Alias	eIF4G 3; eIF4GII; eIF-4G 3
Transcripts	ENSG00000075151
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O43432
HGNC ID	HGNC:3298
VEGA ID	OTTHUMG00000002624
OMIM ID	603929
String ID	9606.ENSP00000383274
PharmGKB ID	PA27724

Target gene [EIF4G3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010855	chr1	11			11	View
1012193	chr1	3	4		7	View
1400282	chr1	7	3		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of EIF4G3 expression and immune infiltrating cell level correlation result in HBV+ samples
EIF4G3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).