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HBV Target gene Detail Information

> ELOVL5 Gene Search Result


Gene Information
Gene Name ELOVL5
Gene ID 60481
Gene Full Name ELOVL fatty acid elongase 5
Gene Alias HELO1; SCA38; dJ483K16.1
Transcripts ENSG00000012660
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9NYP7
HGNC ID HGNC:21308
VEGA ID OTTHUMG00000016249
OMIM ID 611805
String ID 9606.ENSP00000359956
Drugbank ID BE0009331
PharmGKB ID PA128394703
Target gene [ELOVL5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1016214 chr6 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of ELOVL5 expression and immune infiltrating cell level correlation result in HBV+ samples
ELOVL5 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).