Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> EPB41 Gene Search Result


Gene Information
Gene Name EPB41
Gene ID 2035
Gene Full Name erythrocyte membrane protein band 4.1
Gene Alias HE; EL1; 4.1R
Transcripts ENSG00000159023
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Plasma membrane;Cytokinetic bridge;Cytosol;Mitotic spindle;Nuclear bodies;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Gene Function Suppressor gene
Uniport_ID P11171
HGNC ID HGNC:3377
VEGA ID OTTHUMG00000003644
OMIM ID 130500
String ID 9606.ENSP00000345259
PharmGKB ID PA27810
Target gene [EPB41] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010738 chr1 9 2 11 View
1010739 chr1 9 2 11 View
1015186 chr1 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of EPB41 expression and immune infiltrating cell level correlation result in HBV+ samples
EPB41 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).