HBV Target gene Detail Information

> EPS8 Gene Search Result

Gene Information

Gene Name	EPS8
Gene ID	2059
Gene Full Name	epidermal growth factor receptor pathway substrate 8
Gene Alias	DFNB102
Transcripts	ENSG00000151491
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q12929
HGNC ID	HGNC:3420
VEGA ID	OTTHUMG00000168787
OMIM ID	600206
String ID	9606.ENSP00000281172
PharmGKB ID	PA27839

Target gene [EPS8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000140	chr12	3124	1402	1073	5599	View
1007617	chr12	4	21		25	View
1007623	chr12	4	21		25	View
1015555	chr12	1	1		2	View
1403253	chr12	4	21		25	View
1403876	chr12	4	21		25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of EPS8 expression and immune infiltrating cell level correlation result in HBV+ samples
EPS8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).