HTLV1 Target gene Detail Information

> FADS3 Gene Search Result

Gene Information

Gene Name	FADS3
Gene ID	3995
Gene Full Name	fatty acid desaturase 3
Gene Alias	CYB5RP; LLCDL3
Transcripts	ENSG00000221968
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoli fibrillar center;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9Y5Q0
HGNC ID	HGNC:3576
VEGA ID	OTTHUMG00000167500
OMIM ID	606150
String ID	9606.ENSP00000278829
PharmGKB ID	PA27975

Target gene [FADS3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003163	chr11	27	96	55	178	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of FADS3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FADS3 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of FADS3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FADS3 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of FADS3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
FADS3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).