HTLV1 Target gene Detail Information

> FAM131B Gene Search Result


Gene Information
Gene Name FAM131B
Gene ID 9715
Gene Full Name family with sequence similarity 131 member B
Transcripts ENSG00000159784
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q86XD5
HGNC ID HGNC:22202
VEGA ID OTTHUMG00000152697
OMIM ID 619282
String ID 9606.ENSP00000410603
PharmGKB ID PA162386065
Target gene [FAM131B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6015432 chr7 14 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of FAM131B expression and immune infiltrating cell level correlation result in HTLV1+ samples
FAM131B expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of FAM131B expression and immune infiltrating cell level correlation result in HTLV1+ samples
FAM131B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).