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EBV Target gene Detail Information

> FAM172A Gene Search Result


Gene Information
Gene Name FAM172A
Gene ID 83989
Gene Full Name family with sequence similarity 172 member A
Gene Alias Toupee; C5orf21
Transcripts ENSG00000113391
Virus EBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;Predicted to be secreted;
HPA Protein Class Info Predicted intracellular proteins, Predicted secreted proteins
Gene Function Suppressor gene
Uniport_ID Q8WUF8
HGNC ID HGNC:25365
VEGA ID OTTHUMG00000131329
String ID 9606.ENSP00000379294
PharmGKB ID PA162387241
Target gene [FAM172A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000444 chr5 18 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of FAM172A expression and immune infiltrating cell level correlation result in EBV+ samples
FAM172A expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of FAM172A expression and immune infiltrating cell level correlation result in EBV+ samples
FAM172A expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of FAM172A expression and immune infiltrating cell level correlation result in EBV+ samples
FAM172A expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of FAM172A expression and immune infiltrating cell level correlation result in EBV+ samples
FAM172A expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of FAM172A expression and immune infiltrating cell level correlation result in EBV+ samples
FAM172A expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of FAM172A expression and immune infiltrating cell level correlation result in EBV+ samples
FAM172A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).