HBV Target gene Detail Information

> FBXL17 Gene Search Result

Gene Information

Gene Name	FBXL17
Gene ID	64839
Gene Full Name	F-box and leucine rich repeat protein 17
Gene Alias	Fbl17; Fbx13; FBXO13
Transcripts	ENSG00000145743
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9UF56
HGNC ID	HGNC:13615
VEGA ID	OTTHUMG00000159785
OMIM ID	609083
String ID	9606.ENSP00000437464
PharmGKB ID	PA134920563

Target gene [FBXL17] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008140	chr5	19	2	1	22	View
1010228	chr5	3	4	6	13	View
1014731	chr5			3	3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FBXL17 expression and immune infiltrating cell level correlation result in HBV+ samples
FBXL17 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).