Home
Virus
Gene
Disease
Dataset
Download
Help
 
HTLV1 Target gene Detail Information

> FCGR3A Gene Search Result


Gene Information
Gene Name FCGR3A
Gene ID 2214
Gene Full Name Fc fragment of IgG receptor IIIa
Gene Alias CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA
Transcripts ENSG00000203747
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID P08637
HGNC ID HGNC:3619
VEGA ID OTTHUMG00000034466
OMIM ID 146740
String ID 9606.ENSP00000356946
Drugbank ID BE0002097
PharmGKB ID PA28065
FDA Approved Drug Margetuximab-cmkb
Target gene [FCGR3A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6018403 chr1 9 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of FCGR3A expression and immune infiltrating cell level correlation result in HTLV1+ samples
FCGR3A expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of FCGR3A expression and immune infiltrating cell level correlation result in HTLV1+ samples
FCGR3A expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of FCGR3A expression and immune infiltrating cell level correlation result in HTLV1+ samples
FCGR3A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).