HBV Target gene Detail Information

> FDPS Gene Search Result

Gene Information

Gene Name	FDPS
Gene ID	2224
Gene Full Name	farnesyl diphosphate synthase
Gene Alias	FPS; FPPS; POROK9
Transcripts	ENSG00000160752
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P14324
HGNC ID	HGNC:3631
VEGA ID	OTTHUMG00000013909
OMIM ID	134629
String ID	9606.ENSP00000349078
Drugbank ID	BE0000776
PharmGKB ID	PA28075

Target gene [FDPS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009475	chr1	15			15	View
1011644	chr1	7		1	8	View
1401402	chr1	7		1	8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FDPS expression and immune infiltrating cell level correlation result in HBV+ samples
FDPS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).